Cannabis May Provide Resillience Against Stress-Related Patholigies, According to New Study

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Cannabis May Provide Resillience Against Stress-Related Patholigies, According to New Study

Maintaining “robust” encendocannabinoid signaling – which can be done through through the intake of cannabinoids – may providecannabisbud protection against stress and stress-related disorders, according to a new study published in the journal Seminars in Immunology, and published online by the National Institute of Health.

According to the study, “CB1 receptor-endocannabinoid signaling is activated by stress and functions to buffer or dampen the behavioral and endocrine effects of acute stress.”

It continues; “Its role in regulation of neuronal responses is more complex. Chronic variable stress exposure reduces endocannabinoid-CB1 receptor signaling and it is hypothesized that the resultant deficiency in endocannabinoid signaling contributes to the negative consequences of chronic stress. On the other hand, repeated exposure to the same stress can sensitize CB1 receptor signaling, resulting in dampening of the stress response.”

Researchers conclude that; “Data are reviewed that support the hypothesis that CB1 receptor signaling is stress responsive and that maintaining robust endocannabinoid/CB1 receptor signaling provides resilience against the development of stress-related pathologies.”

Given that cannabis activates and regulates the body’s cannabinoid receptors, this study gives strong indication that cannabis consumption may provide a defense against stress, and stress-related disorders.


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The study was conducted by researchers at the Medical College of Wisconsin’s Neuroscience Research Center and Department of Pharmacology and Toxicology.

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1 Comment

  • NorCalNative
    June 5, 2014

    The stress-relief properties of cannabis is why ALL cannabis use is medicinal.

    And, while it’s nice to see a study showing this result, every old pot head or experienced cannabis user has known about and appreciated the stress-relief from cannabis for as long as they’ve been using cannabis.

    Stress sets the body up for other conditions of poor health and it makes sense to reduce the amount of stress in our lives in any way possible. Go Team Cannabis!

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