New Study: Cannabis May Protect Liver From Alcohol Related Damage

A new study published in the journal Free Radical Biology and Medicine has found that cannabidiol, a compound found in cannabis, can prevent damage to the liver caused by alcohol consumption. budcannabis

According to the study’s abstract; “Acute alcohol drinking induces steatosis, and effective prevention of steatosis can protect liver from progressive damage caused by alcohol. Increased oxidative stress has been reported as one mechanism underlying alcohol-induced steatosis.”

It continues; “We evaluated whether cannabidiol, which has been reported to function as an antioxidant, can protect the liver from alcohol-generated oxidative stress-induced steatosis. Cannabidiol can prevent acute alcohol-induced liver steatosis in mice, possibly by preventing the increase in oxidative stress and the activation of the JNK MAPK pathway. Cannabidiol per se can increase autophagy both in CYP2E1-expressing HepG2 cells and in mouse liver. Importantly, cannabidiol can prevent the decrease in autophagy induced by alcohol.”

Researchers conclude that these results “show that cannabidiol protects mouse liver from acute alcohol-induced steatosis through multiple mechanisms including attenuation of alcohol-mediated oxidative stress, prevention of JNK MAPK activation, and increasing autophagy.”

The study was conducted by researchers at the School of Public Health at Sun Yat-sen University in China, the Mount Sinai School of Medicine in New York, and the State Key Laboratory of Oncology at the Sun Yatsen University Cancer Center in China.

TheJointBlog

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    • Storm Crow on April 29, 2014 at 12:52 pm
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    Cannabis also prevents the brain damage that alcohol causes! See NORML’s “Marijuana May Offset Alcohol-Induced Cognitive Impairment Among Teens”, or the PubMed study “White Matter Integrity in Adolescents with Histories of Marijuana Use and Binge Drinking “. More can be found in “Granny Storm Crow’s List”- online and on Facebook.

  1. What I knew with Cannabis it is a Psychoactive drug and never knew it has this active substance that can protect our liver.

    Just like to share, if you want easy and fastest ways to protect your liver read my article: 17 Ways to Protect Your Liver – http://monstertnutrition.com/shop.php?a=%20ways-to-protect-your-liver

    • scott steven on February 11, 2014 at 6:32 pm
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    very good. I been making phoenix tears since 2000 legally. Mine has killed cancer in a number of people I know. It has kept me cancer-free since 2000 when my MD DR. prescribed it to me…I’m 60 now but don’t feel it.

    • Anonymous on January 20, 2014 at 5:00 am
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    I have liver damage is the medicine out yet if so hit me on fb bubba middle

    I will even do a stu
    dy if needed thank you

      • Carney-Stratakis on January 27, 2014 at 12:36 pm
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      I have a cancer that I’ve researching how cannabis might help with. The $100,000 medication they’ve offered me acts as a suppressant of the JNK MAPK pathways . . . exactly what cannabis studies are showing to block.

      I am still looking into the science on whether there is a high enough dose of liquid cannabis to reduce tumors. As a side note I had 2/3rds of my liver cut out 2 years ago because of invasive tumors (not liver cancer). The liver grew back in four months time and during that whole time I was on liquid cannabis. People tell me I look better than I did before cancer (5 years ago) and I tell them it is medical marijuana (in gel cap form).

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