Cannabidiol Can Kill Multiple Myeloma Cells
Multiple myeloma is a type of cancer that begins in the bone marrow, and has a median survival rate of around 3 years. According to a study published in the most recent issue of the International Journal of Cancer, cannabidiol, a compound found in cannabis, can slow, and even kill multiple myeloma cancer cells.
“Multiple myeloma (MM) is a plasma cell (PC) malignancy characterised by the accumulation of a monoclonal PC population in the bone marrow (BM). Cannabidiol (CBD) is a non-psychoactive cannabinoid with antitumoural activities”, begins the study’s abstract.
After studying the effects of cannabidiol on multiple myeloma cells, researchers found that; “CBD by itself or in synergy with BORT strongly inhibited growth, arrested cell cycle progression and induced MM cells death by regulating the ERK, AKT and NF-κB pathways with major effects in TRPV2+ cells.” They conclude that; “These data provide a rationale for using CBD to increase the activity of proteasome inhibitors in MM.”
The study, which validates a recent National Institute of Health study which also found that cannabidiol can inhibit cancer cells, was conducted by researchers at the School of Pharmacy at the University of Camerino in Italy.