Study: Targeting Cannabinoid Receptors May Provide Treatment Option for Alcoholism

A study published this month in the journal Pharmacology Biochemistry and Behavior has found that targeting¬†the body’s cannabinoid receptors mayalcohol provide a viable treatment option for alcoholism.

For the study, a compound (BCP) meant to mimic the effects of cannabis¬†“was used to investigate the role of the CB2¬†receptors in mediating alcohol intake and ethanol-induced conditioned place preference (EtOH-CPP) and sensitivity in mice. The effect of BCP on alcohol intake was evaluated using the standard two-bottle choice drinking method. The mice were presented with increasing EtOH concentrations and its consumption was measured daily. Consumption of saccharin and quinine solutions was measured following the EtOH preference tests. Finally, the effect of BCP on alcohol reward and sensitivity was tested using an unbiased EtOH-CPP and loss of righting-reflex (LORR) procedures, respectively.”

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New Study: Cannabis May Treat Brain Damage Caused by Heavy Alcohol Consumption

A new study published last week by the journal Pharmacology Biochemistry and Behavior has found that cannabis braindamagemay reduce the brain damage associated with long-term, heavy alcohol consumption.

According to researchers, “the current study aimed to advance the preclinical development of transdermal delivery of cannabidiol (CBD) for the treatment of alcohol-induced neurodegeneration.”

For the study, rat models were treated with two forms of administered cannabidiol (a compound of cannabis), through a transdermal gel, and an intraperitoneal injection.

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