Cannabinoids May Treat Oxidative Stress-Related Neurodegenerative Disorders, Says New Study

Cannabinoids have therapeutic potential in oxidative stress-related acute or chronic neurodegenerative disorders from stroke, multiple sclerosis and traumatic brain injury to Alzheimer`s and Parkinson`s diseases, according to a new study.

The study, conducted by researchers at the National Institute of Health (NIH) and Rutgers New Jersey Medical School, is being published in the journal Antioxidants & Redox Signaling, and has been e-published ahead of print by NIH’s PubMed.gov.

According to the study’s abstract:

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Study: Cannabinoids May Help Treat Traumatic Brain Injury

Cannabinoids may provide a potential treatment option for traumatic brain injury, according to new research.

The study was published in the latest issue of the journal Frontiers in Pharmacology, and published online by the U.S. National Institute of Health.

“The endogenous cannabinoid (endocannabinoid) system regulates a diverse array of physiological processes and unsurprisingly possesses considerable potential targets for the potential treatment of numerous disease states, including two receptors (i.e., CB1 and CB2 receptors) and enzymes regulating their endogenous ligands N-arachidonoylethanolamine (anandamide) and 2-arachidonyl glycerol (2-AG)”, states the study’s abstract.

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Multiple Changes to Washington’s Medical Cannabis Law Now in Effect

washington-flagSeveral provisions found in Washington State’s Senate Bill 5052, signed by Governor Jay Inslee in April, go into effect today, July 24th. Although most of the changes are regressive, such as eliminating in-home collective gardens, post traumatic stress disorder and traumatic brain injuries have been added to the list of qualifying medical cannabis conditions.

One change that goes into effect today is a ban on the use of butane in the production of hash oil, unless the individual or company producing the substance has a license from the state’s Liquor Control Board. This means that currently operating medical cannabis dispensaries will need to cease producing and (unless it was produced before the new law went into effect) selling butane hash oil, commonly referred to as BHO.

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Cannabis Can Rescue Learning and Memory After a Traumatic Brain Injury, According to Study

A new study injurypublished in the journal Annals of Clinical and Translational Neurology has found that activation of the body’s cannabinoid receptors – something done naturally by cannabis – can rescue learning and memory after a traumatic brain injury.

For the study, researchers “tested the hypothesis that posttraumatic brain injury administration of a cannabinoid 1 receptor agonist can rescue deficits in learning and memory. Young adult male rats were subjected to a moderately severe controlled cortical impact brain injury, with a subset given postinjury i.p. injections of a cannabinoid receptor agonist.’

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Study: THC Increases Survival Rates in People that Experience Traumatic Brain Injury

The presence of tetrahydrocannabinol (THC) in the system is associated with increased survival rates in those who experience traumatic brain injury (TBI), according to a new study published intbi the American Journal of Surgery.

“Traumatic brain injury (TBI) is associated with significant morbidity and mortality”, says Dr. Binh Minh Nguyen, the study’s lead author. “Several studies have demonstrated neuroprotective effects of cannabinoids. The objective of this study was to establish a relationship between the presence of a positive toxicology screen for tetrahydrocannabinol (THC) and mortality after TBI.”

After examining 446 individuals – 18.4% of which had THC in their system – it was found that the mortality rate for the THC positive group was just 2.4% (two deaths total), compared with 11.5% (forty two deaths total) in the THC negative group; a 479% decrease.

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