Cannabinoids May Treat Oxidative Stress-Related Neurodegenerative Disorders, Says New Study

Cannabinoids have therapeutic potential in oxidative stress-related acute or chronic neurodegenerative disorders from stroke, multiple sclerosis and traumatic brain injury to Alzheimer`s and Parkinson`s diseases, according to a new study.

The study, conducted by researchers at the National Institute of Health (NIH) and Rutgers New Jersey Medical School, is being published in the journal Antioxidants & Redox Signaling, and has been e-published ahead of print by NIH’s PubMed.gov.

According to the study’s abstract:

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Cannabis May Protect Neurons and Improve Motor Recovery During an Ischemic Stroke, Finds Study

cannabisohyeahA new study published in the Journal of Neurochemistry, and published online by the U.S. National Institute of Health, has found that cannabis may protect neurons and greatly improve motor recovery during an ischemic stroke. An ischemic stroke is caused by damage to the brain due to an interruption of its blood supply.

“Brain ischemia produces neuronal cell death and the recruitment of pro-inflammatory cells”, states the study’s abstract. “In turn, the search for neuroprotection against this type of insult has rendered results involving a beneficial role of endocannabinoid receptor agonists in the Central Nervous System.”

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Study: Cannabis Can Attenuate Damage, Improve Memory Retention Following Stroke

Marijuana_Plants-3A new study published by the journal Life Science, and published online by the National Institute of Health, has found that cannabinoid receptor activation – something done naturally by cannabis – can attenuate damage and improve memory retention following a stroke.

“We have recently demonstrated that treatment with a cannabinoid CB2 agonist was protective in a mouse middle cerebral artery occlusion model of cerebral ischemia/reperfusion injury”, begin’s the study’s abstarct. “The present study aimed to determine whether these protective effects of CB2 agonism would extend to a mouse photoinjury model of permanent ischemia and determine associated alterations in cognition and infarct size.

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New Study: Cannabis May Protect Against, Treat Symptoms of Stroke

A recent study published by the National Institute of Health and the journal Translational Stroke Research has found that activation of the body’s cannabinoidcannabisplant receptors can reduce the harmful effects of strokes, and can even prevent them entirely.

For the study researchers at the Department of Pathology at Temple University School of Medicine used mouse models to examine the effects of activating the body’s cannabinoid receptors on transient middle cerebral artery occlusion/reperfusion injury (MCAO/R). They found that; “In conclusion, administration of the CB2R agonist/CB1R antagonist combination causes a significant reduction in infarct size in the MCAO/R model.”

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