Study: Cannabinoids May Treat Depression-Like Behavior Caused by Social Isolation Stress

A study published in the journal Brain Research Bulletin has found that cannabinoids may treat depression-like behavior induced by social isolation stress.

Social Isolation Stress“Social isolation stress (SIS) paradigm is a chronic stress procedure able to induce profound behavioral and neurochemical changes in rodents and evokes depressive and anxiety-like behaviors”, begins the study’s abstract.

“Recent studies demonstrated that the cannabinoid system plays a key role in behavioral abnormalities such as depression through different pathways; however, there is no evidence showing a relation between SIS and the cannabinoid system.”

With that in mind, this particular study “investigated the role of the cannabinoid system in depressive-like behavior and anxiety-like behavior of IC animals.”

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