seizures Archives - TheJointBlog

Study: CBD Oil ‘Highly Promising’ as Treatment for Pediatric Epilepsy

January 29, 2016

By Paul Armentano, NORML Deputy Director

The administration of cannabis oil extracts high in cannabidiol reduces seizure frequency in children with intractable epilepsy, according to clinical data published online ahead of print in the journal Seizure.

Israeli researchers retrospectively evaluated the effects of CBD oil in a multicenter cohort of 74 patients with intractable epilepsy. Participants in the trial were resistant to conventional epilepsy treatment and were treated with CBD extracts for a period of at least three months. Extracts in the study were provided by a pair of Israeli-licensed growers and were standardized to possess a CBD to THC ratio of 20 to 1.

Study: CBD Can Prevent Seizures in Those with Chronic Epilepsy, Decrease Neuronal Damage Caused by Seizures

December 17, 2015August 28, 2015

A new study published recently by the International Journal of Clinical and Experimental Medicine has found that cannabidiol (CBD), a compound found in cannabis, can prevent seizures in those with chronic epilepsy, and can decreased neuronal damage caused by seizures. The study was also published by the U.S. National Institute of Health.

“The study was designed to investigate the effect of various concentrations of cannabidiol (CBD) in rats with chronic epilepsy”, states the study’s abstract. “The chronic epilepsy rat model was prepared by intraperitoneally injecting pentylenetetrazole to the rats pre-treated with CBD (10, 20 and 50 mg/kg) for 28 consecutive days.”

Cannabidiol Protects Against Cocaine-Induced Seizures, Says National Institute of Health Study

August 24, 2015August 23, 2015

Cannabidiol (CBD), a major non-psychotomimetic constituent of the cannabis plant, protects against cocaine-induced seizures, according to a study published by the U.S. National Institute of Health, and published in print by the journal Neurotoxicology.

“[Cannabidiol] has therapeutic potential for certain psychiatric and neurological disorders”, states the study’s researchers. “Studies in laboratory animals and limited human trials indicate that CBD has anticonvulsant and neuroprotective properties. Its effects against cocaine neurotoxicity, however, have remained unclear.”

Nebraska Senate Votes 44 to 2 to Study Cannabis Oil

May 22, 2015

A legislative proposal that would commission the University of Nebraska to study the effectiveness of low-THC cannabis oil in the treatment of seizure disorders has passed Nebraska’s full Senate with a 44 to 2 vote.

“LB 390 creates the Medical Cannabidiol Pilot Study within the University of Nebraska Medical Center for patients who suffer from severe and untreatable or treatment-resistant epileptic seizures”, according to the legislative intent for the bill, introduced by Senator Sue Crawford. “It allows access to low-THC cannabidiol oil for patients under the supervision of a neurologist at the University of Nebraska Medical Center. Under LB 390, it shall be an affirmative and complete defense to prosecution if the defendant suffers from intractable seizures and is an active participant in the study or if the defendant is the parent or legal guardian of such an individual.”

Cannabis Associated With Seizure Control In Treatment-Resistant Epilepsy, Finds Study

April 23, 2015

By Paul Armentano, NORML

The administration of oral cannabis extracts is associated with the mitigation of seizures in adolescents with epilepsy, according to clinical data published this month in the journal Epilepsy & Behavior.

Researchers from the Colorado Children’s Hospital in Denver performed a retrospective chart review of 75 children provided cannabis extracts. Authors reported that 57 percent of subjects showed some level of improvement in seizure control while 33 percent reported a greater than 50 percent reduction in seizure frequency.

Cannabis Can Successfully Treat Epilepsy in Children, Says New Study

December 22, 2013December 18, 2013

A new study published in this month’s issue of the journal Epilepsy Behavior has found that many parents with epileptic children are turning to cannabis-based medicines to treat their seizures, and in a large majority of instances, it’s successful in doing so.

“Severe childhood epilepsies are characterized by frequent seizures, neurodevelopmental delays, and impaired quality of life. In these treatment-resistant epilepsies, families often seek alternative treatments”, begins the study’s abstract. “This survey explored the use of cannabidiol-enriched cannabis in children with treatment-resistant epilepsy.”

CBDV Suppresses Seizures, Says New Study

December 1, 2013November 29, 2013

A new study published by the National Institute of Health has found that cannabidivarin (CBDV) – a non-psychoactive compound found naturally in cannabis – can effectively decrease the severity of seizures, and in many instances suppress them entirely.

According to the study’s abstract; “Consistent with previous findings, CBDV significantly decreased PTZ-induced seizure severity (median: 3.25) and increased latency to the first sign of seizure.”

Cannabis Can Stop Seizures, Treat Epilepsy, According to New Study

October 16, 2013October 16, 2013

A new study published in this month’s issue of the British Journal of Pharmacology has found that cannabis can stop seizures due to its “significant anticonvulsant effects”.

For the study researchers used an extract made from the whole cannabis plant, and used the substance on a number of animal models – using rats and mice – and found that the extract was able to effectively stop seizures.

New Study: Cannabis Can Stop Seizures

October 14, 2013August 15, 2013

A new study published by the British Journal of Pharmacology has found that cannabis can stop seizures due to its “significant anticonvulsant effects”.