Study: Cannabidiol Induces ‘Rapid-Acting Antidepressant-Like Effects’

brightleafCannabidiol (CBD) – a compound found in the cannabis plant – induces “rapid-acting antidepressant-like effects”, according to a new study being published in the April issue of the journal Neuropharmacology.

“Cannabidiol (CBD), the main non-psychotomimetic component of marihuana, exhibits anxiolytic-like properties in many behavioural tests, although its potential for treating major depression has been poorly explored”, begins the study’s abstract. “Moreover, the mechanism of action of CBD remains unclear. Herein, we have evaluated the effects of CBD following acute and chronic administration in the olfactory bulbectomy mouse model of depression (OBX), and investigated the underlying mechanism.”

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Cannabis May Improve Motor Symptoms, Stimulate Neuroprotective Processes In Those With Huntington’s Disease

A study published this month in the journal Neuropharmacology, and published online by the U.S. National Institute of Health, has found that prolongednhlegalization administration of a compound meant to mimic the effects of cannabis can improve motor symptoms and stimulate neuroprotective processes in those with Huntington’s disease.

“Huntington’s disease (HD) is a devastating neurodegenerative disease characterized by a progressive decline in motor abilities, as well as in cognitive and social behaviors”, claims the study. “Most of these behavioral deficits are recapitulated in the R6/1 transgenic mouse, which can therefore be used as an experimental model to identify the neurobiological substrates of HD pathology and to design novel therapeutic approaches.”

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New Study Finds Cannabis May Have Neuroprotective Effects

A new study, published in the August edition of Neuropharmacology, has found that cannabis may serve as a cannabisneuroprotectantneuroprotectant.

Researchers from the University Hospital Puerta de Hierro Majadahonda, in Madrid, Spain, examined the effect of CBD when applied to a hypoxic-ischemic (HI) brain injury model (most common in instances such as cardiac arrest, when blood flow stops or slows, and oxygen can’t effectively reach the brain). The scientists interrupted carotid blood flow and reduced oxygen intake levels to 10% in animal subjects for 30 minutes. The damage of the HI injury was immense:

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New Study Indicates Cannabis May Reduce Aggression, Improve Social Interactions

A new study published by the journal Neuropharmacology has found that cannabinoids may reduce aggression, and improve social interactions.Marijuana_Plants-3

For the study, researchers “examined the role of cannabinoid CB1 receptors (CB1r) in aggressive behavior”, and found that a compound meant to mimic THC (a prime compound of cannabis) “significantly decreased the aggression levels” of the mice that it was administered to. The researchers also examined mice which were bred without CB1 receptors, and found them to be more inherently aggressive than normal mice.

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