life science Archives - TheJointBlog

Study Finds THC Inhibits the Growth of Melanoma Skin Cancer

September 7, 2015 by Anthony Martinelli

Tetrahydrocannabinol (THC) inhibits melanoma tumor growth, according to a study published in the October, 2015 issue of the journal Life Science, and published online by the National Institute of Health. According to the Skin Cancer Foundation, melanoma is the most dangerous form of skin cancer, killing nearly 10,000 people annually.

For the study, researchers examined the effect of cannabis-derived THC on the growth of melanoma “in vitro and in vivo in wild type (WT) and CB1/CB2-receptor deficient mice (Cnr1/2^-/-). Next, they “evaluated the role of the endogenous cannabinoid system by studying the growth of chemically induced melanomas, fibrosarcoma and papillomas in WT and Cnr1/2^-/- mice.”

Study: Cannabis Can Attenuate Damage, Improve Memory Retention Following Stroke

August 30, 2015June 6, 2015 by Anthony Martinelli

A new study published by the journal Life Science, and published online by the National Institute of Health, has found that cannabinoid receptor activation – something done naturally by cannabis – can attenuate damage and improve memory retention following a stroke.

“We have recently demonstrated that treatment with a cannabinoid CB2 agonist was protective in a mouse middle cerebral artery occlusion model of cerebral ischemia/reperfusion injury”, begin’s the study’s abstarct. “The present study aimed to determine whether these protective effects of CB2 agonism would extend to a mouse photoinjury model of permanent ischemia and determine associated alterations in cognition and infarct size.

Study: THC Inhibits the Growth of Melanoma

May 10, 2015May 1, 2015 by Anthony Martinelli

∆⁹-tetrahydrocannabinol (THC) inhibits melanoma tumor growth, according to a study published in the most recent issue of the journal Life Science, and published online by the National Institute of Health.

For the study, researchers “examined the effect of THC, which binds to CB receptors (CB1, CB2), on the growth of the mouse melanoma… in vitro and in vivo in wild type (WT) and CB1/CB2-receptor deficient mice (Cnr1/2^-/-). Next we evaluated the role of the endogenous cannabinoid system by studying the growth of chemically induced melanomas, fibrosarcoma and papillomas in WT and Cnr1/2^-/- mice.”