Study: THC May Inhibit Growth of Endometrial Cancer

9-tetrahydrocannabinol (THC) may inhibit the migration of endometrial cancer cells, according to a study published by the journal Oncology Letters and epublished by the National Institute of Health.

“Limited therapeutic interventions are clinically available for treating aggressive endometrial cancer (EC)”, begins the study’s abstract. “Therefore, effective therapies are urgently required.” The present study “investigated the role of ∆9-tetrahydrocannabinol (THC), which is reported to impact proliferative and migratory activities during impairment of cancer progression.”

In the study, “cell migration in response to THC was measured using transwell assays. Using western blot analysis, the levels of cannabinoid receptors in EC tissues were detected and pathways leading to the inhibition of cell migration by THC on human EC cells were determined.”

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Study: CBD May Help Treat, and Cause the Death of, Endometrial Cancer

CBD (cannabidiol) and CBD-rich extracts may provide a potential treatment option for endometrial cancer, according to a new study published by the Journal of Physiology and Biochemistry, and published online by the U.S. National Institute of Health.

Endometrial cancer,

“Among a variety of phytocannabinoids, Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most promising therapeutic compounds”, begins the study’s abstract. “Besides the well-known palliative effects in cancer patients, cannabinoids have been shown to inhibit in vitro growth of tumor cells. Likewise, the major endocannabinoids (eCBs), anandamide (AEA) and 2-arachidonoylglycerol (2-AG), induce tumor cell death.”

The purpose of the present study “was to characterize cannabinoid elements and evaluate the effect of cannabinoids in endometrial cancer cell viability.” Endometrial cancer is a variety of cancer that begins in the lining of the uterus.

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