Study: Cannabinoids May Prevent Depressive and PTSD-Like Symptoms Following Severe Stress

Cannabinoids may prevent both depressive and PTSD-like symptoms following exposure to severe stress, according to a new study being published by the journal Progress in Neuro-Psychopharmacology & Biological Psychiatry.

“Posttraumatic stress disorder (PTSD) is a debilitating condition highly comorbid with depression”, begins the abstract of the study, which was also published by the U.S. National Institute of Health. “The endocannabinoid (eCB) system and brain-derived neurotrophic factor (BDNF) are suggestively involved in both disorders.” For the study, researchers “examined whether cannabinoids can prevent the long-term depressive-like symptoms induced by exposure to the shock and situational reminders (SRs) model of PTSD.”

Researchers administered a compound meant to mimic the effects of natural cannabinoids in rats two hours after a severe shock. “Cannabinoids prevented the shock/SRs-induced alterations in social recognition memory, locomotion, passive coping, anxiety-like behavior, anhedonia, fear retrieval, fear extinction and startle response as well as the decrease in BDNF levels in the hippocampus and prefrontal cortex (PFC)”, states the study. “Furthermore, significant correlations were found between depressive-like behaviors and BDNF levels in the brain.”

Read moreStudy: Cannabinoids May Prevent Depressive and PTSD-Like Symptoms Following Severe Stress

Watermelon Marijuana Strain Overview

Watermelon is a heavy indica that’s the perfect treat to cap off the night.

Watermelon

Watermelon is an indica-dominant marijuana strain (typically 80/20) that is known for having thick, dense nuggets, similar to Granddaddy Purple. The flavor is that of berries and grape, with a similar smell that lingers in the room well after a smoke session.

Watermelon is a vaunted strain by growers, mostly because of its high yield compared to other strains; but, of course, also because of its potency and flavor.

Some of its top effects include:

  • Relaxation
  • Happiness
  • Sleepiness
  • Increased Appetite

Some of the top medical ailments it helps with are:

  • Insomnia
  • Depression
  • Stress
  • Anxiety
  • Post traumatic stress disorder (PTSD)
  • Pain and also
  • Headaches/Migraines

Reviews:

At the time of publication Watermelon has 78 reviews on Leafly with an average score of 4.4 out of 5.

Where to find it

If you live in a state where cannabis is legal, you may want to check out Leafly’s strain finder. This feature can use your exact location to find the closet cannabis store or dispensary to you that is currently carrying the Watermelon marijuana strain; you can also look for a variety of other strains.

Click here for this strain finder.

Study: Cannabinoids a Treatment Option for Diabetes-Associated Depression

Diabetes-Associated DepressionThe journal European Neuropsychopharmacology has published a study showing that cannabinoids may provide a treatment option for depression associated with diabetes.

“The pathophysiology associated with increased prevalence of depression in diabetics is not completely understood, although studies have pointed the endocannabinoid system as a possible target”, researchers state. With this in mind, they “aimed to investigate the role of this system in the pathophysiology of depression associated with diabetes.”

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Study: Cannabidiol Induces ‘Rapid-Acting Antidepressant-Like Effects’

brightleafCannabidiol (CBD) – a compound found in the cannabis plant – induces “rapid-acting antidepressant-like effects”, according to a new study being published in the April issue of the journal Neuropharmacology.

“Cannabidiol (CBD), the main non-psychotomimetic component of marihuana, exhibits anxiolytic-like properties in many behavioural tests, although its potential for treating major depression has been poorly explored”, begins the study’s abstract. “Moreover, the mechanism of action of CBD remains unclear. Herein, we have evaluated the effects of CBD following acute and chronic administration in the olfactory bulbectomy mouse model of depression (OBX), and investigated the underlying mechanism.”

Read moreStudy: Cannabidiol Induces ‘Rapid-Acting Antidepressant-Like Effects’

Government-Funded Study: Cannabis May Treat Depression Caused By Chronic Stress

Researchers atDepression conceptual design isolated on white background. Low mood concept the University of Buffalo, with a grant from the National Institute of Mental Health, have found that cannabis may provide a treatment option for depression that results from chronic stress.

“In the animal models we studied, we saw that chronic stress reduced the production of endocannabinoids, leading to depression-like behavior,” said senior research scientist Samir Haj-Dahmane, PhD, in a press release sent out this week. “Using compounds derived from cannabis — marijuana — to restore normal endocannabinoid function could potentially help stabilize moods and ease depression”, he says.

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Study: No Longitudinal Association Between Cannabis Use and Depression

By Paul Armentano, NORML

TEL AVIV, ISRAEL — Cannabis use is not associated joint with increased incidences of major depression, according to longitudinal data published online ahead of print in the Journal of Affective Disorders.

An international team of investigators from Israel and Canada assessed the association between cannabis use, major depressive disorder (MDD) and bipolar disorder (BP) in a three-year prospective study.

Authors determined that future incidence of MDD was not higher among cannabis users compared to nonusers. They reported: “Our results show no significant association between cannabis use and the incidence of major depression.

Read moreStudy: No Longitudinal Association Between Cannabis Use and Depression

New Study: Cannabis May Treat Stress-Related Illnesses Such as Depression

A study published in this month’s issue of the British Journal of Pharmacology has found that cannabis may treat stress-related illnesses “with a neuroinflammatory component”, such as depression.healthmeup.com

For the study researchers conducted various experiments with animal models (in this instance, rats) and found that activating certain cannabinoid receptors was successful in reversing the inflammatory response caused by stress.

Read moreNew Study: Cannabis May Treat Stress-Related Illnesses Such as Depression