Study: Cannabis Can Cause Death of Colon Cancer Cells

According to a new study published by the journal Cannabis and Cannabinoid Research, and published online by the U.S. National Institute of Health, cannabis can cause the death of colon cancer cells, implying that it may be a potential treatment option for the disease.

“Colorectal cancer remains the third most common cancer diagnosis and fourth leading cause of cancer-related mortality worldwide”, begins the abstract of the study. “Purified cannabinoids have been reported to prevent proliferation, metastasis, and induce apoptosis in a variety of cancer cell types. However, the active compounds from Cannabis sativa flowers and their interactions remain elusive.” This study was “aimed to specify the cytotoxic effect of C. sativa-derived extracts on colon cancer cells and adenomatous polyps by identification of active compound(s) and characterization of their interaction.”

For the study, ethanol extracts of C. sativa were “analyzed by high-performance liquid chromatography and gas chromatograph/mass spectrometry and their cytotoxic activity was determined using alamarBlue-based assay (Resazurin) and tetrazolium dye-based assay (XTT) on cancer and normal colon cell lines and on dysplastic adenomatous polyp cells.”

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Study: CBD a “Therapeutic Candidate for Stroke Prevention”

Cannabidiol (CBD) may help to prevent strokes, according to a new study published by the U.S. National Institute of Health.

“The endocannabinoid system (ECS) regulates functions throughout human physiology, including neuropsychiatric, cardiovascular, autonomic, metabolic, and inflammatory states”, begins the study’s abstract, which was published in-print by the journal Cannabis and Cannabinoid Research. “The complex cellular interactions regulated by the ECS suggest a potential for vascular disease and stroke prevention by augmenting central nervous and immune cell endocannabinoid signaling.”

Cannabidiol (CBD), a nonpsychoactive constituent of Cannabis, “is an immediate therapeutic candidate both for potentiating endocannabinoid signaling and for acting at multiple pharmacological targets.” According to reseachers, this “speculative synthesis explores the current state of knowledge of the ECS and suggests CBD as a therapeutic candidate for stroke prevention by exerting favorable augmentation of the homeostatic effects of the ECS and, in turn, improving the metabolic syndrome, while simultaneously stalling the development of atherosclerosis.”

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New Cannabis and Cannabinoid Research Journal Launching in the Fall

Cannabis cannabiscuresnauseaand Cannabinoid Research, a new peer-reviewed, open access journal, will launch this fall as the world’s first journal dedicated to the scientific, medical, and psychosocial exploration of clinical cannabis, cannabinoids, and the biochemical mechanisms of endocannabinoids.

“Launching in fall 2015, the Journal will be the premier open source for authoritative cannabis and cannabinoid research, discussion, and debate” states a recent press release from Mary Ann Liebert, Inc., the publishing company behind the new journal, which will be published “under the Creative Commons Attribution 4.0 (CC BY) license to ensure broad dissemination and participation.”

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