Study: Cannabinoids a Potential Treatment for Disorders Associated with Traumatic Memories

Cannabinoids provide a potential treatment option for disorders associated with traumatic memories, according to a new study.

The study was published in the journal European Neuropsychopharmacology, and e-published ahead of print by the U.S. National Institute of Health.

“Memory reconsolidation is the process in which reactivated long-term memory becomes transiently sensitive to amnesic agents”, states the study’s abstract. “We evaluated the ability of post reactivation administration of the mTOR inhibitor rapamycin, separately and in combination with the cannabinoid CB1/2 receptor agonist WIN55,212-2 (WIN) [meant to mimic the effects of natural cannabinoids]”. This was given “systemically or specifically into the hippocampal CA1 area, basolateral amygdala (BLA) or insular cortex (IC), to reduce inhibitory avoidance fear in rats.”

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New Study: Cannabinoids a Promising Tool in Treatment of Breast and Prostate Cancer

Prostate CancerA new study being published in the upcoming issue of the journal Expert Opinion on Investigational Drugs, and published online ahead of print by the U.S. National Institute of Health, has found that cannabinoids may be a promising tool for the treatment of breast and prostate cancer.

According to the study’s abstract; “The aim of this review is to evaluate the promising chemotherapeutic utility of phytocannabinoids, endocannabinoids, and synthetic cannabinoids in breast and prostate cancer.”

In their evaluation, researchers found that; “Cannabinoids, in particular the non-psychoactive CBD, may be promising tools in combination therapy for breast and prostate cancer, due to their direct antitumor effects, their ability to improve the efficacy of conventional antitumor drugs and their usefulness as palliative treatment.”

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Cannabinoids May Improve Night Vision, Study Finds

Night VisionBy ScienceDaily.com

Scientists used a variety of methods to test how tadpoles react to visual stimuli when they’ve been exposed to increased levels of exogenous or endogenous cannabinoids. Exogenous cannabinoids are artificially introduced drugs, whereas endogenous cannabinoids occur naturally in the body.

They found that, contrary to what they expected, activating cannabinoid signaling in tadpoles actually increased the activity in their retinal ganglion cells (RGCs), which are responsible for transmitting information about light detection from the eye to the brain. Previous studies found that cannabinoids typically work to reduce neurotransmission, not increase it.

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Study: Cannabinoids a Treatment Option for Diabetes-Associated Depression

Diabetes-Associated DepressionThe journal European Neuropsychopharmacology has published a study showing that cannabinoids may provide a treatment option for depression associated with diabetes.

“The pathophysiology associated with increased prevalence of depression in diabetics is not completely understood, although studies have pointed the endocannabinoid system as a possible target”, researchers state. With this in mind, they “aimed to investigate the role of this system in the pathophysiology of depression associated with diabetes.”

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Study: Cannabinoids Enhances Visual Responses

Vision1A new study being published in the next issue of the journal eLife, and published online ahead of print by the U.S. National Institute of Health, has found that cannabinoids can enhance visual responses.

“Type 1 cannabinoid receptors (CB1Rs) are widely expressed in the vertebrate retina but the role of endocannabinoids in vision is not fully understood”, the study’s abstract begins. “Here we identified a novel mechanism underlying a CB1R-mediated increase in retinal ganglion cell (RGC) intrinsic excitability acting through AMPK-dependent inhibition of NKCC1 activity.”

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Study: Cannabinoids Reverse the Effects of Stress on Neurocognitive Performance

stressA new study published in the July, 2016 issue of the journal Learning & Memory, and published online by the U.S. National Institute of Health, has found that cannabinoids reverse the effects of stress on neurocognitive performance in young adults.

“Early life stress (ES) significantly increases predisposition to psychopathologies [mental illness or mental distress]”, states the study’s abstract. “Here we examined whether cannabinoids administered during “late adolescence” (extensive cannabis use in humans at the ages 18-25) could reverse the long-term adverse effects of ES on neurocognitive function in adulthood.”

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Study: Cannabinoids are Safe, Effective for Pain Treatment

By Paul Armentano, NORML

Medical-MarijuanaCannabinoids are safe and effective for the treatment of chronic pain, according to the results of a systematic review of randomized controlled trials published in the Journal of Neuroimmune Pharmacology.

Investigators from Dalhousie University in Halifax, Nova Scotia and McGill University in Montreal evaluated the results of 11 placebo-controlled trials conducted between the years 2010 and 2014. Trials assessed the use of various types of cannabinoid preparations, including herbal cannabis, liquid and oral cannabis extracts, and nabilone (a synthetic analog of THC), in pain treatment.

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Cannabis Can Cause Cancer Cells to Burst, According to Study

cannabinoidsCannabinoids can increase a cancer cell’s susceptibility to cytolysis, which occurs when a cell bursts due to an imbalance, according to a study published by the journal Biochemical Pharmacology, and published online by the National Institute of Health.

“Using lung cancer cell lines (A549, H460) and metastatic cells derived from a lung cancer patient, the present study addressed the impact of cannabinoid-induced ICAM-1 on cancer cell adhesion to lymphokine-activated killer (LAK) cells and LAK cell-mediated cytotoxicity”, the study’s abstract states.

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64 Studies That Show Cannabis Can Treat Various Cancers

Cannabis, and the cannabinoid compounds found within it, has been shown through a large cannabisplantamount of scientific, peer-reviewed research to be effective at treating a wide variety of cancers, ranging from brain cancer to colon cancer. Below is a list of over 60 studies that demonstrate the vast anti-cancer properties of cannabis.

Studies showing cannabis may combat brain cancer:

      • Cannabidiol (CBD) inhibits the proliferation and invasion in U87-MG and T98G glioma cells. Study published in the Public Library of Science journal in October 2013.
      • Tetrahydrocannabinol (THC) can kill cancer cells by causing them to self-digest. Study published in the Journal of Clinical Investigation in September 2013.

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      Comprehensive Study Finds Cannabis May Treat Various Diseases, Particularly Headaches

      flower-power-2A new comprehensive meta-study published by the journal Headache, and published online by the National Institute of Health, has found that cannabis may be effective at treating a variety of diseases, particularly chronic pain disorders such as headaches.

      “The use of cannabis, or marijuana, for medicinal purposes is deeply rooted though history, dating back to ancient times”, claims the study’s abstract. “It once held a prominent position in the history of medicine, recommended by many eminent physicians for numerous diseases, particularly headache and migraine. Through the decades, this plant has taken a fascinating journey from a legal and frequently prescribed status to illegal, driven by political and social factors rather than by science. However, with an abundance of growing support for its multitude of medicinal uses, the misguided stigma of cannabis is fading, and there has been a dramatic push for legalizing medicinal cannabis and research.”

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