Study: Cannabigerol May Treat Neuroinflammation and Oxidative Stress

According to a new study published by the International Journal of Molecular Sciences, the cannabis compound cannabigerol “may be a potential treatment against neuroinflammation and oxidative stress.”

“Inflammation and oxidative stress play main roles in neurodegeneration”, states the study’s abstract. “Interestingly, different natural compounds may be able to exert neuroprotective actions against inflammation and oxidative stress, protecting from neuronal cell loss. Among these natural sources, Cannabissativa represents a reservoir of compounds exerting beneficial properties, including cannabigerol (CBG), whose antioxidant properties have already been demonstrated in macrophages.”

With this in mind, researches “aimed to evaluate the ability of CBG to protect motor neurons against the toxicity induced from the medium of LPS-stimulated RAW 264.7 macrophages.”

Read moreStudy: Cannabigerol May Treat Neuroinflammation and Oxidative Stress

Study: Cannabigerol Effective At Stimulating Appetite

The cannabis compound cannabigerol (CBG) is effective at stimulating appetite without any negative side effects, according to a newCannabigerol study published by the journal Psychopharmacology; it was epublished ahead of print by the U.S. National Institute of Health. The study was published shortly after a separate study (also published by Psychopharmacology) which found that two other cannabis compounds – tetrahydrocannabinol (THC) and cannabidiolic acid (CBDA) – are also effective at stimulating appetite.

“The appetite-stimulating properties of cannabis are well documented and have been predominantly attributed to the hyperphagic activity of the psychoactive phytocannabinoid, ∆9-tetrahydrocannabinol (∆9-THC)”, states the study’s abstract. “However, we have previously shown that a cannabis extract devoid of ∆9-THC still stimulates appetite, indicating that other phytocannabinoids also elicit hyperphagia. One possible candidate is the non-psychoactive phytocannabinoid cannabigerol (CBG), which has affinity for several molecular targets with known involvement in the regulation of feeding behaviour.”

Read moreStudy: Cannabigerol Effective At Stimulating Appetite

Study: Cannabigerol May Prevent Colon Cancer

A new study published by the Oxford journal Carcinogenesis, and published online by the U.S. National Institute of Health, has foundcannabiscoloncancer that the cannabis compound cannabigerol can prevent the progression of cancer cells formed in the colon.

“Cannabigerol (CBG) is a safe non-psychotropic Cannabis-derived cannabinoid which interacts with specific targets involved in carcinogenesis [the creation of cancer cells]”, begins the study’s abstract. “Here, we investigated whether CBG protects against colon tumorigenesis.”

After studying the effect of CBG on colon cancer cells, researchers found that; “In vivo, CBG inhibited the growth of xenograft tumors as well as chemically-induced colon carcinogenesis. CBG hampers colon cancer progression in vivo and selectively inhibits the growth of colorectal cancer cells.”

Read moreStudy: Cannabigerol May Prevent Colon Cancer

New Study Finds Cannabis May Provide Treatment for Skin Diseases

A new study, recently published online in the British Journal of Pharmacology, details how cannabinoids can play a role in the treatment of skin diseases.saved15

Researchers looked at the impact of phytocannabinoids (plant-derived cannabinoids, rather than synthetic counterparts) on epigenetic regulation of skin differentiation genes.

The study found that both cannabidiol (CBD) and cannabigerol (CBG), “significantly reduced the expression of all genes tested via increased DNA methylation for keratin 10 gene”.

Read moreNew Study Finds Cannabis May Provide Treatment for Skin Diseases