Study: CBD Reduces Salience and Pleasantness of Cigarettes

According to a new study published by the journal Addiction, a single dose of cannabidiol (CBD) reduces the salience and pleasantness of cigarette cues, compared with a placebo.

“Cannabidiol (CBD), a non-intoxicating cannabinoid, may be a promising novel smoking cessation treatment due to its anxiolytic properties, minimal side-effects and research showing it may modify drug cue salience”, begins the abstract of this “Randomized, double-blind crossover study with a fixed satiated session followed by two overnight abstinent sessions.”

For the study, researchers “used an experimental medicine approach with dependent cigarette smokers to investigate if (1) overnight nicotine abstinence, compared with satiety, will produce greater attentional bias (AB), higher pleasantness ratings of cigarette-related stimuli and increased craving and withdrawal; (2) CBD in comparison to placebo, would attenuate AB, pleasantness of cigarette-related stimuli, craving and withdrawal and not produce any side-effects.”

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