Single Dose of CBD Reduces Blood Pressure, Finds Randomized, Placebo-Controlled, Double-Blind, Crossover Study

Just a single dose of cannabidiol (CBD) reduces blood pressure, indicating it may play a role in the treatment of cardiovascular disorders, according to a new study published by the journal JCI Insight.

According to researchers, the aim of this study “was to investigate if CBD reduces BP [blood pressure] in humans.” To determine this, “Nine healthy male volunteers were given 600 mg of CBD or placebo in a randomized, placebo-controlled, double-blind, crossover study. Cardiovascular parameters were monitored using a finometer and laser Doppler.”

CBD “reduced resting systolic BP (–6 mmHg; P < 0.05) and stroke volume (–8 ml; P < 0.05), with increased heart rate (HR) and maintained cardiac output. Subjects who had taken CBD had lower BP (–5 mmHg; P < 0.05, especially before and after stress), increased HR (+10 bpm; P < 0.01), decreased stroke volume (–13 ml; P < 0.01), and a blunted forearm skin blood flow response to isometric exercise.’ In response to cold stress, “subjects who had taken CBD had blunted BP (–6 mmHg; P < 0.01) and increased HR (+7 bpm; P < 0.05), with lower total peripheral resistance.”

Read moreSingle Dose of CBD Reduces Blood Pressure, Finds Randomized, Placebo-Controlled, Double-Blind, Crossover Study