Cannabinoids May Attenuate Negative Effects of Morphine on Magnocellular Neurons

cannabinoidsA new study published in the Iran Journal of Basic Medical Science, and published online by the U.S. National Institute of Health, has found that cannabinoids may prevent the negative effects of morphine on magnocellular neurons. Magnocellular neurons are neuroendocrine cells (cells that receive neuronal input) located in the hypothalamus (a portion of the brain), and are among the largest cells in the brain.

“Opioids and cannabinoids are two important compounds that have been shown to influence the activity of magnocellular neurons (MCNs) of supraoptic nucleus (SON)”, state’s the study’s objective statement. “The interaction between opioidergic and cannabinoidergic systems in various structures of the brain and spinal cord is now well established, but not in the MCNs of SON.”

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