Study: THC May Safely and Effectively Treat Anorexia Nervosa Symptoms

THC may be a safe and effective treatment for the psychological symptoms of anorexia nervosa, according to a new study published by The Israeli Journal of Psychiatry and Related Sciences.

For the study, researchers at Hebrew University and the Eating Disorders Institution at the University of Haifa “evaluated the effect of low doses of oral Δ9-THC on self-reported symptoms of patients suffering from chronic anorexia nervosa (AN).”

Nine female subjects over 18 years of age participated in the study. “Six were diagnosed according to DSM-IV criteria with AN restrictive type and three with active AN binge-purge type.” Their mean age was 45.0±3.2 years and their BMI was 16.1±1.6 kg/M2. They completed questionnaires before and after treatment with Δ9-THC (1 mg/day for one week and 2 mg/day for three weeks). “The primary outcome was improvement in the way patients perceived their eating behavior.”

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Study: Cannabinoids Attenuate Hyperactivity and Weight Loss in Anorexia

According to a new study, cannabinoids can attenuate (reduce the effects of) hyperactivity and body weight loss in activity-based anorexia.

The study, published by the British Journal of Pharmacology, was epublished ahead of print by the U.S. National Institute of Health.

“Anorexia nervosa (AN) is a serious psychiatric condition characterized by excessive body weight loss and disturbed perceptions of body shape and size, often associated with excessive physical activity”, states the study’s abstract. “There is currently no effective drug-related therapy of this disease and this leads to high relapse rate. Clinical data suggest that a promising therapy to treat and reduce reoccurrence of AN may be based on the use of drugs that target the endocannabinoid (EC) system [such as cannabinoids], which appears dysregulated in AN patients.”

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