Study: Marijuana Consumption Reduces Symptoms of Crohn’s Disease, May Lead to Remission

Marijuana consumption reduces the symptoms associated with Crohn’s disease, and can even lead to its remission, according to new research published on the website of the National Institutes of Health, which will be in print soon in the journal Clinical Gastroenterology and Hepatology.cannabis-crohns

The study, which was conducted by researchers at the Meir Medical Center, Department of Gastroenterology and Hepatology in Israel, examined 21 subjects with Crohn’s disease who weren’t responsive to conventional treatments. According to the the study, ” Patients were randomly assigned to groups given cannabis, twice daily, in the form of cigarettes containing 11.5 mg of tetrahydrocannabinol (THC) or placebo containing cannabis flowers from which the THC had been extracted. Disease activity and laboratory tests were assessed during 8 weeks of treatment and 2 weeks thereafter.”

In the study, “complete remission” was achieved by five out of the eleven patients who received THC, compared to just one out of ten of those who received a placebo. Complete remission is defined as a reduction in patient CDAI score by more than 150 points – the CDIA is a research tool used to quantify the symptoms of Crohn’s disease.

In addition, a clinical response (defined as a decrease in CDAI score of >100) was observed in 10/11 subjects in the cannabis group, compared to 4/10 in the placebo group.

According to the study, “Three patients in the cannabis group were weaned from steroid dependency. Subjects receiving cannabis reported improved appetite and sleep, with no significant side effects.”

TheJointBlog

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    • Ally on January 1, 2014 at 1:59 am
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    Sorry about your sister, R.

    I have Crohns and I misspell it the time. Maybe its just because of the weed? No other problems to report.

    • Johna Osgood on June 16, 2013 at 10:44 pm
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    There is a genetic association with Crohn’s disease, primarily with variations of the NOD2 gene and its protein, which senses bacterial cell walls. Siblings of affected individuals are at higher risk.’^,-

    My own web blog
    http://www.caramoanpackage.com/index.php/

    • R. Joseph Newton on May 13, 2013 at 9:13 pm
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    Some citations would be helpful. Your social media person misspelled Crohn’s in the Facebook lead for this article. This is important. My eldest sister was severely hampered in her enjoyment of life by Crohn’s Disease, and died from complications. I have at least one other sibling diagnosed wit the condition. Unfortunately, they are unlely to place great credence in a site with a definite agenda, such as this one.

    1. Hi – Sources are hyperlinked throughout the article, as they are with most any of the articles we publish where we include sources. Here is the study:

      http://www.ncbi.nlm.nih.gov/pubmed/23648372

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