CBD may be a useful treatment for various breast cancer subtypes, according to a new study published by the journal The Breast.
“Studies have emphasized an antineoplastic effect of the non-psychoactive, phyto-cannabinoid, Cannabidiol (CBD)”, begins the study’s abstract, which was epublished ahead of print by the National Institute of Health. “However, the molecular mechanism underlying its antitumor activity is not fully elucidated. Herein, we have examined the effect of CBD on two different human breast cancer cell lines”.
In both cell lines, “CBD inhibited cell survival and induced apoptosis in a dose dependent manner as observed by MTT assay, morphological changes, DNA fragmentation and ELISA apoptosis assay.”
The results “suggest that CBD treatment induces an interplay among PPARγ, mTOR and cyclin D1 in favor of apoptosis induction in both ER-positive and triple negative breast cancer cells, proposing CBD as a useful treatment for different breast cancer subtypes.”
The full study, conducted by researchers at Alexandria University in Egypt, can be found by clicking here.