Study: Cannabigerol May Treat Neuroinflammation and Oxidative Stress

“Inflammation and oxidative stress play main roles in neurodegeneration”, states the study’s abstract. “Interestingly, different natural compounds may be able to exert neuroprotective actions against inflammation and oxidative stress, protecting from neuronal cell loss. Among these natural sources, Cannabissativa represents a reservoir of compounds exerting beneficial properties, including cannabigerol (CBG), whose antioxidant properties have already been demonstrated in macrophages.”

With this in mind, researches “aimed to evaluate the ability of CBG to protect motor neurons against the toxicity induced from the medium of LPS-stimulated RAW 264.7 macrophages.”

Using MTT assay (a colorimetric assay for assessing cell metabolic activity), they “observed that CBG pre-treatment was able to reduce the loss of cell viability induced by the medium of LPS-stimulated macrophages in NSC-34 cells”, among other positive changes.

Researchers conclude by stating that “All together, these results indicated the neuroprotective effects of CBG, that may be a potential treatment against neuroinflammation and oxidative stress.”

The full study can be found by clicking here.