A new study published in the journal Obesity, and published online by the National Institute of Health, has found that cannabis use is associated with a lower body mass index (BMI), which results in lower insulin resistance.
For the study, researchers set out to “ascertain the relationship between cannabis use, obesity, and insulin resistance” by analyzing “786 Inuit adults from the Nunavik Inuit Health Survey”. Information on cannabis use was obtained “from a self-completed, confidential questionnaire”, and “fasting blood glucose and insulin and homeostasis model assessment of insulin resistance (HOMA-IR) served as surrogate markers of insulin resistance.” In addition, analysis of “covariance and multivariate logistic regression ascertained relationships between cannabis use and outcomes.”
According to researchers; “Cannabis use was highly prevalent in the study population (57.4%) and was statistically associated with lower body mass index (BMI) (P < 0.001), lower % fat mass (P < 0.001), lower fasting insulin (P = 0.04), and lower HOMA-IR (P = 0.01), after adjusting for numerous confounding variables.”
Researchers found that the effects of cannabis use on insulin resistance was due to the decrease in BMI. According to the National Institute of Diabetes and Digestive and Kidney Diseases; “Insulin resistance is a condition in which the body produces insulin but does not use it effectively. When people have insulin resistance, glucose builds up in the blood instead of being absorbed by the cells, leading to type 2 diabetes or prediabetes.”
The study concludes; “Cannabis use was associated with lower BMI, and such an association did not occur through the glucose metabolic process or related inflammatory markers. The association between cannabis use and insulin resistance was mediated through its influence on weight.”
The study can be found by clicking here.