New Study Finds Cannabinoids An Effective Treatment For Multiple Sclerosis

marijuana card

New Study Finds Cannabinoids An Effective Treatment For Multiple Sclerosis

A new study published in this month’s issue of the journal European Neurology, and published online by the U.S. National Institute of Health,stock2 has found that Sativex – a medicinal spray made from the cannabis plant – is an effective and safe treatment option for “moderate to severe multiple sclerosis spasticity (MSS)”.

According to researchers: “Nabiximols (Sativex®), a cannabinoid-based oromucosal spray, is an add-on therapy for patients with moderate to severe multiple sclerosis spasticity (MSS) resistant to other medications. The primary objective was to provide real-life observational data of clinical experience of nabiximols in contrast to formal clinical trials of effectiveness.”

Researchers used an “observational, prospective, multicenter, non-interventional” research method with “a follow-up period of 3-4 months”; in total, 335 patients were assessed.

After conducting the study, it was concluded that; “Real-life data confirm nabiximols as an effective and well-tolerated treatment option for resistant MSS in clinical practice.”

The study was conducted by researchers at the Neurological Rehabilitation Center Quellenhof in Germany.


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A study published earlier this year by the journal Expert Review of Neurotherapeutics came to a similar conclusion about Sativex, finding it to be an effective treatment for multiple sclerosis spasticity.

TheJointBlog

2 Comments

  • scott steven
    February 18, 2014

    read this this morning:
    Colo. pot aids kids with seizures, worries doctors
    Families with kids with seizures move to Colorado for special pot, but doctors are concerned
    Associated Press
    By Nicholas Riccardi, Associated Press 5 hours ago

    Colo. pot aids kids with seizures, worries doctors
    .

    View photo

    In this Feb. 7, 2014 photo, Matt Figi hugs and tickles his once severely-ill 7-year-old daughter Charlotte, as they wander around inside a greenhouse for a special strain of medical marijuana known as Charlotte’s Web, which was named after the girl early in her treatment, in a remote spot in the mountains west of Colorado Springs, Colo. A few years ago, Charlotte’s doctors were out of ideas to help her. Suffering from a rare disorder known as Dravet’s syndrome, Charlotte had as many as 300 grand mal seizures a week, was confined to a wheelchair, went into repeated cardiac arrest and could barely speak. Now Charlotte is largely seizure-free, able to walk, talk and feed herself, with her parents attributing her dramatic improvement to this strain of medical cannabis. (AP Photo/Brennan Linsley)

    COLORADO SPRINGS, Colo. (AP) — The doctors were out of ideas to help 5-year-old Charlotte Figi.

    Suffering from a rare genetic disorder, she had as many as 300 grand mal seizures a week, used a wheelchair, went into repeated cardiac arrest and could barely speak. As a last resort, her mother began calling medical marijuana shops.

    Two years later, Charlotte is largely seizure-free and able to walk, talk and feed herself after taking oil infused with a special pot strain. Her recovery has inspired both a name for the strain of marijuana she takes that is bred not to make users high — Charlotte’s Web — and an influx of families with seizure-stricken children to Colorado from states that ban the drug.

    “She can walk, talk; she ate chili in the car,” her mother, Paige Figi, said as her dark-haired daughter strolled through a cavernous greenhouse full of marijuana plants that will later be broken down into their anti-seizure components and mixed with olive oil so patients can consume them. “So I’ll fight for whoever wants this.”

    Doctors warn there is no proof that Charlotte’s Web is effective, or even safe.

    In the frenzy to find the drug, there have been reports of non-authorized suppliers offering bogus strains of Charlotte’s Web. In one case, a doctor said, parents were told they could replicate the strain by cooking marijuana in butter. Their child went into heavy seizures.

    “We don’t have any peer-reviewed, published literature to support it,” Dr. Larry Wolk, the state health department’s chief medical officer, said of Charlotte’s Web.

    Still, more than 100 families have relocated since Charlotte’s story first began spreading last summer, according to Figi and her husband and the five brothers who grow the drug and sell it at cost through a nonprofit. The relocated families have formed a close-knit group in Colorado Springs, the law-and-order town where the dispensary selling the drug is located. They meet for lunch, support sessions and hikes.

    “It’s the most hope lots of us have ever had,” said Holli Brown, whose 9-year-old daughter, Sydni, began speaking in sentences and laughing since moving to Colorado from Kansas City and taking the marijuana strain.

    Amy Brooks-Kayal, vice president of the American Epilepsy Society, warned that a few miraculous stories may not mean anything — epileptic seizures come and go for no apparent reason — and scientists do not know what sort of damage Charlotte’s Web could be doing to young brains.

    “Until we have that information, as physicians, we can’t follow our first creed, which is do no harm,” she said, suggesting that parents relocate so their children can get treated at one of the nation’s 28 top-tier pediatric epilepsy centers rather than move to Colorado.

    However, the society urges more study of pot’s possibilities. The families using Charlotte’s Web, as well as the brothers who grow it, say they want the drug rigorously tested, and their efforts to ensure its purity have won them praise from skeptics like Wolk.

    For many, Charlotte’s story was something they couldn’t ignore.

    Charlotte is a twin, but her sister, Chase, doesn’t have Dravet’s syndrome, which kills kids before they reach adulthood.

    In early 2012, it seemed Charlotte would be added to that grim roster. Her vital signs flat-lined three times, leading her parents to begin preparing for her death. They even signed an order for doctors not to take heroic measures to save her life again should she go into cardiac arrest.

    Her father, Matt, a former Green Beret who took a job as a contractor working in Afghanistan, started looking online for ways to help his daughter and thought they should give pot a try. But there was a danger: Marijuana’s psychoactive ingredient, THC, can trigger seizures.

    The drug also contains another chemical known as CBD that may have seizure-fighting properties. In October, the Food and Drug Administration approved testing a British pharmaceutical firm’s marijuana-derived drug that is CBD-based and has all its THC removed.

    Few dispensaries stock CBD-heavy weed that doesn’t get you high. Then Paige Figi found Joel Stanley.

    One of 11 siblings raised by a single mother and their grandmother in Oklahoma, Stanley and four of his brothers had found themselves in the medical marijuana business after moving to Colorado. Almost as an experiment, they bred a low-THC, high-CBD plant after hearing it could fight tumors.

    Stanley went to the Figis’ house with reservations about giving pot to a child.

    “But she had done her homework,” Stanley said of Paige Figi. “She wasn’t a pot activist or a hippy, just a conservative mom.”

    Now, Stanley and his brothers provide the marijuana to nearly 300 patients and have a waitlist of 2,000.

    The CBD is extracted by a chemist who once worked for drug giant Pfizer, mixed with olive oil so it can be ingested through the mouth or the feeding tube that many sufferers from childhood epilepsy use, then sent to a third-party lab to test its purity.

    Charlotte takes the medication twice a day. “A year ago, she could only say one word,” her father said. “Now she says complete sentences.”

    The recovery of Charlotte and other kids has inspired the Figis and others to travel the country, pushing for medical marijuana laws or statutes that would allow high-CBD, low-THC pot strains.

    Donald Burger recently urged a New York state legislative panel to legalize medical marijuana while his wife, Aileen, was in the family’s new rental house in Colorado Springs, giving Charlotte’s Web to their daughter Elizabeth, 4. The family only relocated to Colorado after neurologists told them Elizabeth’s best hope — brain surgery — could only stop some of her seizures.

    “It’s a very big strain being away from the rest of our family,” Aileen Burger said recently while waiting for her husband to return from a trip to sell their Long Island house. “But she doesn’t have to have pieces of her brain removed.”

    Ray Mirazabegian, an optician in Glendale, Calif., brought Charlotte’s Web to his state, where medical marijuana is legal. He convinced the Stanley brothers to give him some seeds he could use to treat his 9-year-old daughter Emily, who spent her days slumped on the couch. Now, she’s running, jumping and talking. Mirazabegian is cloning the Charlotte’s Web seeds and has opened the California branch of the Stanleys’ foundation.

    Mirazabegian has begun to distribute the strain to 25 families and has a waitlist of 400. It includes, he said, families willing to move from Japan and the Philippines.

  • Jerry
    April 30, 2014

    My mother has a nuerological disease that has taken her mobility, strengnth and normal life. She is disabled and there is no cure for the disease. We are located in south carolina. My mother has found that marijuana helps with her pain muscle spasms tingeling and numbness. The substance marijuana is very controlled and banned here in sc. Its a shame that my mother has to purchase street marijuana to help with her disease. The substance is a product of nature which is natural and grows as a vegitative plant. Its scary when this product of nature is illegal and banned . Studies show that marijuana helps medical disorders such as ms. why cant my disabled mother be abl to use medical marijuana for her disease . Come on america open your eyes.

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