Administration of the cannabis compound cannabidiol (CBD) leads to enhanced bone fracture healing, according to a study being published in an upcoming issue of the Journal of Bone and Mineral Research, and published online ahead of print by the National Institute of Health.
“Cannabinoid ligands regulate bone mass, but skeletal effects of cannabis (marijuana and hashish) have not been reported”, states the study’s abstract. “Bone fractures are highly prevalent, involving prolonged immobilization and discomfort. Here we report that the major non-psychoactive cannabis constituent, cannabidiol (CBD), enhances the biomechanical properties of healing rat mid-femoral fractures.”
For the study, researchers examined the ability of CBD to promote skeletal healing in rats with mid-femoral fractures. It was found that; “CBD markedly enhanced the biomechanical properties of the healing femora after 8 weeks.”
According to researchers; “CBD alone is sufficiently effective in enhancing fracture healing”. They note that “Multiple experimental and clinical trials have portrayed CBD as a safe agent suggesting further studies in humans to assess its usefulness for improving fracture healing.”
The study was conducted at the Hebrew University of Jerusalem’s Bone Laboratory to Israel.