New Study: Cannabinoid Receptor Deficiency May Lead to Heart Failure

A new study published in this month’s issue of the International Journal of Cardiology , and published online by the National Institute of Health, has found that cannabinoid receptor deficiency may lead to heart failureWTCannabis. If this is the case, cannabis consumption would combat this failure, given that it naturally activates our body’s cannabinoid receptors.

According to the study, “The endocannabinoid system is known to play a role in regulating myocardial contractility, but the influence of cannabinoid receptor 1 (CB1) deficiency on chronic heart failure (CHF) remains unclear. In this study we attempted to investigate the effect of CB1 deficiency on CHF induced by pressure overload and the possible mechanisms involved.”

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Cannabis Protects Skeleton from Age-Related Bone Loss, According to Studies

In recent years numerous studies have found that cannabis can protect the skeleton against age-related bone loss, including diseases such as osteoporosis. cannabisthc

A 2009 study published by the journal Annals of Medicine found that “the main physiologic involvement of CB2 [cannabinoid receptor type 2] is associated with maintaining bone remodeling at balance, thus protecting the skeleton against age-related bone loss.”

A 2010 study published by the National Institute of Health concludes: “This review summarises in vitro and in vivo findings relating to the influence of cannabinoid ligands on bone metabolism and argues in favour of the exploitation of cannabinoid receptors as targets for both anabolic and anti-resorptive therapy for treatment of complex multifaceted bone diseases such as osteoporosis.”

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High IQ Linked to Increased Drug Use, According to Study

A study published in the Journal of Epidemiology and Community Health found that those with a high IQ as a child are more likely to use illegal drugs as young adults.highiq

For the study, researchers used data from roughly 8,000 people from the British Cohort Study, a large ongoing population study which examines lifetime drug use, socioeconomic factors, and education levels. IQ scores were measured at the ages of 5 and 10; years later, data was gathered on drug use at the age of 16, and again at the age of 30.

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New Report: Legal Cannabis Market Would be Worth Over £1.25 Billion Annually in U.K.

A new report conducted by the Institute for Social and Economic Research has found that cannabis legalization in the United Kingdom could bring in at least £1.25 billioncannabismoney (roughly $1.6 billion) annually in the U.K., including £300 million being saved from reduced enforcement costs.

According to Professor David Nutt, director of the neuropsychopharmacology unit at Imperial College in London, the report provided strong evidence “that the costs of the current punitive approaches to cannabis control are massively disproportionate to the harms of the drug, and shows that more sensible approaches would provide significant financial benefits to the UK as well as reducing social exclusion and injustice”.

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New Study Finds Cannabis May Have Neuroprotective Effects

A new study, published in the August edition of Neuropharmacology, has found that cannabis may serve as a cannabisneuroprotectantneuroprotectant.

Researchers from the University Hospital Puerta de Hierro Majadahonda, in Madrid, Spain, examined the effect of CBD when applied to a hypoxic-ischemic (HI) brain injury model (most common in instances such as cardiac arrest, when blood flow stops or slows, and oxygen can’t effectively reach the brain). The scientists interrupted carotid blood flow and reduced oxygen intake levels to 10% in animal subjects for 30 minutes. The damage of the HI injury was immense:

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Cannabis Kills Brain Cancer Cells, According to Study

A study published in the Journal of Clinical Investigation found that THC (delta-9-tetrahydrocannabinol) – a prime component of cannabismarijuana-leaf – can kill brain cancer cells by causing them to self-digest.

Researchers for the study examined mice subjects which were implanted with human cancer cells, as well as several human subjects with brain tumors, and found that THC causes brain cancer cells to undergo a process called autophagy; according to WebMD, autophagy is the “breakdown of a cell that occurs when the cell essentially self-digests.”

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New Study: Exercise Increases THC Concentrations in Regular Cannabis Consumers

According to a new study published in the journal Drug and Alcohol Dependence, exercise can increase the concentration of THC in the blood of cannabis consumers.hightimes

For the study, “cannabis users completed 35 min of exercise on a stationary bicycle in either a fed or overnight fasted state.” Following this, “Plasma cannabinoid levels were assessed prior to exercise, immediately post-exercise and 2 h post-exercise. Plasma samples were also analyzed for indices of lipolysis (free fatty acids (FFA) and glycerol).”

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New Study: Cannabis May Treat Brain Damage Caused by Heavy Alcohol Consumption

A new study published last week by the journal Pharmacology Biochemistry and Behavior has found that cannabis braindamagemay reduce the brain damage associated with long-term, heavy alcohol consumption.

According to researchers, “the current study aimed to advance the preclinical development of transdermal delivery of cannabidiol (CBD) for the treatment of alcohol-induced neurodegeneration.”

For the study, rat models were treated with two forms of administered cannabidiol (a compound of cannabis), through a transdermal gel, and an intraperitoneal injection.

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Cannabis Could be Key to Treating Anorexia, According to Study

A new study published by the European Journal of Nuclear Medicine and Molecular Imaging has found that anorexia causes a “widespread transient disturbance” in the body’s endocannabinoid system, indicating that cannabcannabisis consumption could solve much of the problem by fixing this disturbance.

According to the study’s abstract; “Using [18F]MK-9470 and small animal positron emission tomography (PET), we investigated for the first time cerebral changes in type 1 cannabinoid (CB1) receptor binding in vivo in the activity-based rat model of anorexia (ABA), in comparison to distinct motor- and food-related control conditions and in relation to gender and behavioural variables.”

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Activation of Cannabinoid Receptors May Treat Alzheimer’s Disease

A new study published by the journal Neurobiology of Aging has found promising evidence to suggest that Alzheimer’s disease is significantly worsened by a deficiency in Medical_Symbolthe body’s cannabinoid receptors, indicating that the disease could be treated with cannabis, which naturally activates these receptors.

For the study, researchers implanted mice with Alzheimer’s disease, and examined a control group compared to a group which was deficient in cannabinoid receptors. Researchers found that the mice which were deficient in a particular cannabinoid receptor “showed impaired learning and memory deficits” compared to the control group.

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