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64 Studies That Show Cannabis Can Treat Various Cancers

Cannabis, and the cannabinoid compounds found within it, has been shown through a large cannabisplantamount of scientific, peer-reviewed research to be effective at treating a wide variety of cancers, ranging from brain cancer to colon cancer. Below is a list of over 60 studies that demonstrate the vast anti-cancer properties of cannabis.

Studies showing cannabis may combat brain cancer:

      • Cannabidiol (CBD) inhibits the proliferation and invasion in U87-MG and T98G glioma cells. Study published in the Public Library of Science journal in October 2013.
      • Tetrahydrocannabinol (THC) can kill cancer cells by causing them to self-digest. Study published in the Journal of Clinical Investigation in September 2013.

      • CBD is a novel therapeutic target against glioblastoma. Study published in Cancer Research in March 2013.
      • Local delivery of cannabinoid-filled microparticles inhibits tumor growth in a model of glioblastoma multiforme. Study published in Public Library of Science in January 2013.
      • Cannabinoid action inhibits the growth of malignant human glioma U87MG cells. Study published in Oncology Reports in July 2012.
      • Cannabidiol enhances the inhibitory effects of THC on human glioblastoma cell proliferation and survival. Study published in the Molecular Cancer Therapeutics journal in January 2010.
      • Cannabinoid action induces autophagy-mediated cell death in human glioma cells. Study published in The Journal of Clinical Investigation in May 2009.
      • Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. Study published in Cancer Research in March 2008.
      • Cannabinoids and gliomas. Study published in Molecular Neurobiology in June 2007.
      • Cannabinoids inhibit gliomagenesis. Study published in the Journal of Biological Chemistry in March 2007.
      • A pilot clinical study of THC in patients with recurrent glioblastoma multiforme. The results were published in the British Journal of Cancer in June 2006.
      • Cannabidiol inhibits human glioma cell migration through an independent cannabinoid receptor mechanism. Study published in the British Journal of Pharmacology in April 2005.
      • Cannabinoids inhibit the vascular endothelial growth factor pathway (VEGF) in gliomas. Study published in the Journal of Cancer Research in August 2004.
      • Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. Study published in the Journal of Pharmacology in November 2003.
      • Inhibition of glioma growth in vivo by selective activation of the CB2 cannabinoid receptor. Study published in the Journal of Cancer Research in August 2001.

Studies showing cannabis may combat colorectal cancer:

      • Cannabigerol (CBG) can inhibit colon cancer cells. Study published in the Oxford journal Carcinogenesis in October 2014.
      • Inhibition of colon carcinogenesis by a standardised Cannabis Sativa extract with high content of CBD. Study published in Phytomedecine in December 2013.
      • Chemopreventive effect of the non-psychotropic phytocannabinoid CBD on colon cancer. Study published in the Journal of Molecular Medecine in August 2012.
      • Cannabinoids against intestinal inflammation and cancer. Study published in Pharmacology Research in August 2009.
      • Action of cannabinoid receptors on colorectal tumor growth. Study published by the Cancer Center of the University of Texas in July 2008.

Studies showing cannabis may combat blood cancer:

      • The effects of cannabidiol and its synergism with bortezomib in multiple myeloma cell lines. Study published in the International Journal of Cancer  in December 2013.
      • Enhancing the activity of CBD and other cannabinoids against leukaemia. Study published in Anticancer Research in October 2013.
      • Cannabis extract treatment for terminal acute lymphoblastic leukemia of Philadelphia chromosome (Ph1). Study published in Case Reports in Oncology in September 2013.
      • Expression of type 1 and type 2 cannabinoid receptors in lymphoma. Study published in the International Journal of Cancer in June 2008.
      • Cannabinoid action in mantle cell lymphoma. Study published in Molecular Pharmacology in November 2006.
      • THC-induced apoptosis in Jurkat leukemia. Study published in Molecular Cancer Research in August 2006.
      • Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. Study published in Blood American Society of Hemmatology in July 2002.

Studies showing cannabis can combat lung cancer:

      • Cannabinoids increase lung cancer cell lysis by lymphokine-activated killer cells via upregulation of Icam-1. Study published in Biochemical Pharmacology in July 2014.
      • Cannabinoids inhibit angiogenic capacities of endothelial cells via release of tissue inhibitor of matrix metalloproteinases-1 from lung cancer cells. Study published in Biochemical Pharmacology in June 2014.
      • COX-2 and PPAR-γ confer CBD-induced apoptosis of human lung cancer cells. Study published in Molecular Cancer Therapeutics in January 2013.
      • CBD inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1. Study published in the Journal of the Federation of American Societies for Experimental Biology in April 2012.
      • Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non–small cell lung cancer growth and metastasis. Study published in Cancer Prevention Research in January 2011.
      • THC inhibits epithelial growth factor-induced (EGF) lung cancer cell migration in vitro as well as its growth and metastasis in vivo. Study published in the journal Oncogene in July 2007.

Studies showing cannabis may combat stomach cancer:

      • Cannabinoid receptor agonist as an alternative drug in 5-Fluorouracil-resistant gastric cancer cells. Study published in Anticancer Research in June 2013.
      • Antiproliferative mechanism of a cannabinoid agonist by cell cycle arrest in human gastric cancer cells. Study published in the Journal of Cellular Biochemistry in March 2011.

Studies showing cannabis may combat prostrate cancer:

      • Cannabinoids may provide a treatment option for prostate cancer that has become nonresponsive to common therapy, according to a study published in the February issue of the journal Oncology Reports, and published online by the National Institute of Health.
      • Cannabinoids can treat prostate cancer. Study published by the National Institute of Health in October 2013.
      • Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms. Study published in the British Journal of Pharmacology in December 2012.
      • The role of cannabinoids in prostate cancer: Basic science perspective and potential clinical applications. Study published in the Indian Journal of Urology in January 2012.
      • Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent. Study published in Anticancer Research in November 2011.

Studies showing cannabis may combat liver cancer:

      • Involvement of PPARγ in the antitumoral action of cannabinoids on hepatocellular carcinoma (CHC). Study published in Cell Death and Disease in May 2013.
      • Evaluation of anti-invasion effect of cannabinoids on human hepatocarcinoma cells. Study published on the site Informa Healthcare in February 2013.
      • Antitumoral action of cannabinoids on hepatocellular carcinoma. Study published in Cell Death and Differentiation in April 2011.

Studies showing cannabis may combat pancreatic cancer:

      • Cannabinoids inhibit energetic metabolism and induce autophagy in pancreatic cancer cells. Study published in Cell Death and Disease in June 2013.
      • Cannabinoids Induce apoptosis of pancreatic tumor cells. Study published in Cancer Research in July 2006.

Studies showing cannabis may combat skin cancer:

Studies showing cannabis may combat other types of cancer:

      • A study published in the February, 2015 edition of the journal Molecular Oncology, and published online by the National Institute of Health, found that the cannabis compound cannabidiol inhibits the growth and metastasis of highly aggressive breast cancer.
      • Cannabis use is associated with reduced incidences of bladder cancer, according to a study published in the February, 2015 issue of the journal Urology.
      • Bladder: Marijuana reduces the risk of bladder cancer. Study published in the Medscape site in May 2013.
      • Kaposi sarcoma: Cannabidiol inhibits growth and induces programmed cell death in Kaposi sarcoma–associated herpesvirus-infected endothelium. Study published in the journal Genes & Cancer in July 2012.
      • Nose, mouth, throat, ear: Cannabinoids like THC inhibit cellular respiration of human oral cancer cells. Study by the Department of Pediatrics at the State University of New York, published in June 2010.
      • Bile duct: The dual effects of THC on cholangiocarcinoma cells: anti-invasion activity at low concentration and apoptosis induction at high concentration. Study published in Cancer Investigation in May 2010.
      • Ovaries: Cannabinoid receptors as a target for therapy of ovarian cancer. Study published on the American Association for Cancer Research website in 2006.

[Editor’s Note: This article was originally published on October 7th, 2014, but was updated on August 16th, 2015.]

TheJointBlog

About Anthony Martinelli

Anthony, co-founder and Editor-in-Chief of TheJointBlog, has worked closely with numerous elected officials who support cannabis law reform, including as the former Campaign Manager for Washington State Representative Dave Upthegrove. He has also been published by multiple media outlets, including the Seattle Times. He can be reached at TheJointBlog@TheJointBlog.com.

9 comments

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  1. Johnson Oleg

    ” I am here to express my profound warm gratitude to the Rick Simpson hemp oil, which i got from Dr Oscar. I am now leaving a healthy life since the past 1 Year i am now cancer free after the application and usage. You can contact for your medication from via email:droscarhealtcare01@hotmail.com Wish you all the best and a happy healing. Thanks and God Bless you for your help, i will keep on help you to fight cancer in the World.
    Sincerely
    Johnson Oleg
    Chicago

  2. Caroline

    I saw on a Dutch website http://www.stichtingmediwiet.nl/ a non profit foundation for cannabis oil that when you do the oil in suppositories you can take to 1 gram a day (which is recommended with cancer) without the “high” feeling so you won’t be groggy

    God Bless!

  3. David

    Make the oil yourself hun

  4. Matthew Sands

    Decarboxylation – When making cannabis oil for treating late stage cancer it is important to understand decarboxylation. Cannabis in raw/unheated form is primarily THCA, which converts to active THC through heat and time. While some very slow and gradual decarboxylation does occur at temperatures as low as room temp during drying and curing stages of weed preparation it is not until higher heats are encountered that all THCA is converted to THC. If you are making cannabis oil you need to make sure the oil is cooked sufficiently to complete full decarb. Raw cannabis is very beneficial and cannabinoid acids like THCA, along with naturally present terpenes, are believed to be very beneficial with possible anti cancer properties. However, it is active THC, and CBD, that has the majority of clinical and anecdotal evidence supporting its cancer killing effects. So, based on what is currently known, cannabis oil that is most potent in THC content is likely going to be the most potent medicine for curing cancer.
    Raw cannabis in the form of juices and unheated oils are beneficial too and would make a great addition to someone’s treatment, but should not replace cooked cannabis oil, and often require much larger quantities for therapeutic value. Raw or partially cooked oils will contain a wider range of components including cannabinoid acids and terpenes, which are lost when oils are fully cooked, but THC is the most essential cannabinoid for fighting cancer so make sure you decarb your medicine properly to maximise its potency.
    The Rick Simpson method only guarantees partial decarb from the rice cooker stage, and while full decarboxylation can be achieved with the use of a coffee warmer or candle warmer it can take some time to complete this process and other gentle heating devices may not be hot enough. Many of the solvents used have boiling points below the optimum temps for full and rapid decarb. If you do not have a coffee/candle warmer, of even if you do, it is recommended to put your oil in the oven at 110 degrees Celsius for about an hour (optimum temperature range is 110c to 130c/230F to 266F). Visible bubbling will cease when the solvent and water, along with volatile terpenes, are boiled off. But you will see very small pin prick explosions on the surface of the oil during decarboxylation. When this has ceased and there is no activity on the surface of the oil at temps of 110c or above, then you know that decarboxylation is complete. While you want to ensure that temperature does exceed 110 degrees Celsius for decarb, it is also advised to stay below 140 as temps above 140 can lead to a loss of THC through vaporisation (157c+) or degradation to CBN.
    In an ideal world everyone would have access to both raw and cooked cannabis in a well controlled manner, but in this world where oil making can be expensive and risky it is best to make sure your medicine is as potent as it can be to maximise its potential.

  5. Robyn

    My boyfriend has stage 4 asopagas cancer and has spred to lung and kidney. Been doing oils( made on our own) but just found a medical Dr. Havnt got the appointment yet and was wondering if they give the oils or just the canabas? And hes only taking one dose( rice grain size at night because it makes him really groghy and he cant handle the effects. I just read that this small ammount is not enough. He is also on hart meds for a fib and had a blood clott and ison a blood thinner and dont want it to iinterfere with any of that medicine. Also does chemo every two weeks where he bring it home for two days and then has it removed after the two.day period. Im so afraid to give him to much oil because im afraid it may interfere with all else hes taking. Any answers for us would be very much appreciate. Ty in advance from the bottom of our hearts. God Bless.

  6. lisette

    Make it urself

  7. Josephine

    I have bladder cancer, taking the oil, B17, and the cannabis pills,and I also make and drink cannabis tea: is there a study/treatment for bladder cancer: did fine with the lung; no pain, I have stint in my bladder, and they want to do kemo, also talked about removing my bladder: Oh! I am 73yrs young:(smile): I have at least another 10/15 more to enjoy: Please email any deference to med or studies done on and with bladder cancer: Thank You so much for being here:

    1. Leigh

      Josphine, look up Jack Kungel and Trevor Smith. Both have healed themselves of bladder cancer using a combo of cannabis, diet, etc. Their protocols are outlined in the book “Taking Control” by Alyssia Sade on Amazon. (I have no affiliation with her, just have a husband with bladder cancer who is following their protocols.)

  8. sonya lopes

    i am looking for some cannabis oil for my brother he has lung cancer. where can i buy it also need a price please

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