Study: Cannabidiolic Acid (CBDA) Inhibits Highly Aggressive Breast Cancer

Aggressive Breast CancerCannabidiolic acid (CBDA), a little-known compound found in cannabis, can inhibit the migration of highly aggressive breast cancer, according to a study published by the Journal of Natural Medicines and published online by the National Institute of Health.

“The biological activities of CBDA have been attracting increasing attention”, states the study’s researchers, who “identified CBDA as an inhibitor of the migration of MDA-MB-231 cells, a widely used human breast cancer cell line in cancer biology, due to its highly aggressive nature.”

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Study: THC and CBDA Effective in Treating and Preventing Nausea, Stimulating Appetite

cannabiscuresnauseaAdministration of extremely small amounts of THC (tetrahydrocannabinol) and CBDA (cannabidiolic acid) – both cannabis compounds – is effective in treating and preventing nausea, and stimulating appetite, in those going through chemotherapy, a new study has found. The study was published in the journal Psychopharmacology, and published online by the National Institute of Health.

“The objective of this study was to determine the effect of combining subthreshold oral doses of Δ9-tetrahydrocannabinol (THC) and cannabidiolic acid (CBDA) on acute and anticipatory nausea in rat models of conditioned gaping”, states the study’s abstract.

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Study: Cannabinoids May Reduce Inflammation Caused by Mycobacterium

Marijuana_Plants-3Mycobacterium is a genus of Actinobacteria that is known to cause diseases such as tuberculosis and leprosy. According to a new study published in the July issue of the journal Inflammation Research, and e-published ahead of print by the National Institute of Health, cannabinoids may reduce inflammation caused by the bacteria.

For the study, researchers investigated the anti-inflammatory effect of two cannabinoid receptor agonists (meant to mimic the effects of cannabinoids) “in inflammatory experimental model induced by Mycobacterium bovis (BCG).” Mice pretreated with the agonists were induced with “pleurisy or pulmonary inflammation”.

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Study: Cannabinoids Protect Against Alcohol-Induced Liver Disease

liver
(Photo: MedScape.com)

A new study published in the journal Scientific Reports, and published online by the National Institute of Health, has found that activation of the CB2 receptor – done naturally through the consumption of cannabis – can protect against liver inflammation and disease caused by alcohol.

For the study, researchers used mice with alcohol-induced live disease, and administered a cannabinoid receptor agonist (meant to mimic the effects of cannabis) to a portion of them.

They found that the agonist “protected from alcohol-induced liver inflammation and steatosis [fatty liver disease] in wild-type mice”.

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Study: Cannabinoids May Prevent Cartilage Breakdown in those with Osteoarthritis

cannabisA new study published in this month’s issue of the journal Molecular Medicine Reports, and published online by the U.S. National Institute of Health, has found that cannabinoids may prevent cartilage breakdown in those with osteoarthritis.

According to researchers; “A central feature of osteoarthritis (OA) is the loss of articular cartilage, which is primarily attributed to cartilage breakdown.” The current study explored the effects of a synthetic cannabinoid meant to mimic the effects of cannabis-based cannabinoids on preventing this breakdown.

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Study: Cannabinoids Limit Neuroblastoma Cancer Cells

purplecannabisBoth THC (tetrahydrocannabinol) and CBD (cannabidiol) limit neuroblastoma cell proliferation, according to a new study published in the journal Current Oncology, and published online by the U.S. National Institute of Health. Neuroblastoma is an aggressive cancer often found in the small glands on top of the kidneys, though it can also develop in the chest, pelvis, neck, stomach, and bones. Children ages five and younger are most commonly affected.

For the study researchers found that although both THC and CBD helped fight off neuroblastoma cells, CBD was more effective in doing so.

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Study: Cannabis Oil is a Safe and Effective Treatment Option for Alzheimer’s Disease

Alzheimer's DiseaseA study being published in the upcoming issue of the Journal of Alzheimer’s Disease, and e-published ahead of print by the National Institute of Health, has found that cannabis oil is a safe and effective treatment option for Alzheimer’s disease, which affects over 5 million U.S. citizens.

According to researchers, the objective of the study was; “To measure efficacy and safety of medical cannabis oil (MCO) containing THC as an add-on to pharmacotherapy, in relieving behavioral and psychological symptoms of dementia (BPSD).”

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Cannabis Consumption Can Help Prevent Metabolic Syndrome, Finds New Study

smokingjointA new study published in the November issue of the American Journal of Medicine, and published online by the National Institute of Health (NIH), has found that those who currently consume cannabis are considerably less likely to suffer from metabolic syndrome than those who have never used it. Those who have never consumed cannabis are also more likely to have metabolic syndrome than previous cannabis consumers.

According to NIH, Metabolic syndrome is “the name for a group of risk factors that raises your risk for heart disease and other health problems, such as diabetes and stroke. Risk factors include a large waistline, a high triglyceride level, low HDL cholesterol level, high blood pressure and high fasting blood sugar.

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Study: Cannabis Rescues Brain from Alcohol-Induced Neural Damage

neural damageA new study published in the most recent issue of the journal Frontiers in Cellular Neuroscience, and published online by the National Institute of Health, has found that activation of the body’s CB2 receptors – something done naturally by the consumption of cannabis – can rescue the brain from alcohol-induced neural damage.

“Chronic alcohol exposure reduces endocannabinoid activity and disrupts adult neurogenesis in rodents, which results in structural and functional alterations”, claims the study’s abstract. “Cannabinoid receptor agonists [such as cannabis] promote adult neural progenitor cell (NPC) proliferation.”

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Study Finds THC Inhibits the Growth of Melanoma Skin Cancer

cannabudTetrahydrocannabinol (THC) inhibits melanoma tumor growth, according to a study published in the October, 2015 issue of the journal Life Science, and published online by the National Institute of Health. According to the Skin Cancer Foundation, melanoma is the most dangerous form of skin cancer, killing nearly 10,000 people annually.

For the study, researchers examined the effect of cannabis-derived THC on the growth of melanoma “in vitro and in vivo in wild type (WT) and CB1/CB2-receptor deficient mice (Cnr1/2-/-). Next, they “evaluated the role of the endogenous cannabinoid system by studying the growth of chemically induced melanomas, fibrosarcoma and papillomas in WT and Cnr1/2-/- mice.”

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