Study: Cannabinoids May Treat Newborn Brain Injury Caused by Germinal Matrix Hemorrhage

An important new study published by the National Institute of Health has found that activation of the endocannabinoid system – something donemedcannabis naturally by cannabinoids – can attenuate newborn brain injury caused by germinal matrix hemorrhages, which is one of the most common and devastating cerebrovascular events that affect premature infants.

For the study, researchers investigated the effects of a cannabinoid receptor 2 (CB2R) agonist – meant to mimic the effect of cannabinoids – on young rats with germinal matrix hemorrhages (GMH).

“We demonstrated that activation of CB2R played a key role in attenuating brain edema, neuronal degeneration, microglial accumulation and the phosphorylated extracellular signal-regulated kinase (p-ERK) protein level 24 h following GMH”, says researchers.

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