New Study: Cannabinoid Deficiency Worsens Kidney Disease

A new study published in this month’s issue of the journal Kidney International, and published online by the U.S. National Institute of Healthkidney, has found that cannabinoid deficiency worsens diabetic nephropathy, a type of kidney disease, indicating that cannabinoid therapy may provide a treatment.

“A functionally active endocannabinoid system is present within the kidney”, begins the study’s abstract. “The¬†cannabinoid¬†receptor type 2 (CB2) is expressed by both inflammatory cells and podocytes, and its activation has beneficial effects in experimental diabetic nephropathy.” It continues; “To further explore the role of CB2 in diabetic nephropathy, we studied renal functional and structural abnormalities in streptozotocin-induced diabetic CB2 knockout mice.”

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