Indiana: Legislation to Legalize CBD Oil Approved by House Committee

A House committee in Indiana has voted to approve a bill that legalizes cannabdiol (CBD) oil.

The vote on House Bill 1214 comes just a couple days after a Senate committee approved a similar measureHouse Bill 1214 was given approval by the House Committee on Courts and Criminal Code in a unanimous 9 to 0 vote (with four committee members absent).

The approved bill “Specifies that the definition of “industrial hemp” includes the resins of the Cannabis sativa plant. Defines “CBD oil” as a product that contains: (1) not more than 0.3% THC; (2) at least 5% cannabidiol; and (3) no other controlled substances. Legalizes CBD oil”, and “Repeals superseded provisions relating to cannabidiol registration.”

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5 Differences Between THC and CBD

By Robert Bergman, ILoveGrowingMarijuana.com

What are the differences between THC and CBD? Here’s a look.

When you first start smoking weed, you hear the acronyms THC and CBD a lot. Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the two main active cannabinoids in the cannabis plant. There are over one hundre other cannbinoids such as THC-V, THC-A,  and CBN, but if you’re first starting out you should primarily concern yourself with the first two, at least for now. Cannabinoids are these neat little compounds that interact with the endocannabinoids that naturally occur in your body. Though they are both cannabinoids, there are quite a few differences between THC and CBD. For instance…

CBD is Non Psychoactive

This is one of the biggest differences between THC and CBD. THC is the psychoactive cannabinoid; it’s the one that gets you baked. You know that heavy and relaxing feeling that you get after smoking some OG Kush? That can be attributed to THC. CBD on the other hand, is considered to be non psychoactive. This doesn’t mean that you feel nothing after using a high CBD strain or oil, quite the contrary. You won’t experience a noticeable change in your mood, but your body will feel uplifted and just all around. If you were feeling like you’re coming down with a cold prior to smoking, CBD will make you feel better almost instantly. Hence one of the reasons why CBD strains are more popular among medical cannabis users

CBD has Antipsychotic Properties

Sometimes when you smoke a high THC strain you might feel a little off. You might feel a little paranoid, you might have trouble concentrating, maybe your brain feels a little too slowed down, or maybe you feel dizzy. Regardless the effect, it seems that you got too high. The nice thing about CBD is that it can counteract some of those negative effects, and in some cases erase them entirely. High CBD strains are an excellent choice for first timers or those who haven’t figured out what their limits are.

CBD was Discovered First

A lot of people are inclined to believe that THC and CBD were discovered at the same time, or that THC was discovered first  This is another of the biggest differences between THC and CBD. CBD was discovered by American scientist  Roger Adams, a chemist at the University of Illinois, some 20 years before.  THC was actually discovered later by Israeli scientist and college professor Raphael Mechoulam back in the sixties. Mechoulam, better known as the father of cannabinoid research, is quite the extraordinary man.  You can read an interesting interview with Dr. Mechoulam here. Amazing as he is, he is often mistakenly credited with discovering both.

CBD Doesn’t Cause Anxiety

While some strains of high THC cannabis seem to cause endless anxiety in some, CBD does not cause any anxiety. Strains with low amounts of THC and high amounts of CBD are often used to treat anxiety, and I can tell you from experience that they are  extremely good at it. The next time you are feeling some anxiety, try reaching for a CBD strain like  ACDC rather than your usual THC strain. You will notice the difference and you’ll feel a lot better.

CBD Energizes You More

This is one of the differences between THC and CBD that a lot of people don’t know about. After consuming certain strains of THC, you’ve probably felt a little tired. This is because of the psychoactive effects of THC. This is why it is commonly used as a sleep aid. That’s great when you’re looking to go to sleep, but if you’re looking for a strain to pep you up and get you ready for the day, then you should try a CBD strain instead. You will notice that you feel more energized, with none of the fogginess that comes with using some other strains. Here’s another little secret: they’re great for hangovers. They say the best cure for a hangover is time, well add a little CBD to that and you are golden.

So as you can see, CBD has a lot of uses, and is in fact, quite helpful. CBD is what helps to heal the body, hence why it’s so popular among medical users. Try some today and it will change your life, I promise.

Study: CBD a “Therapeutic Candidate for Stroke Prevention”

Cannabidiol (CBD) may help to prevent strokes, according to a new study published by the U.S. National Institute of Health.

“The endocannabinoid system (ECS) regulates functions throughout human physiology, including neuropsychiatric, cardiovascular, autonomic, metabolic, and inflammatory states”, begins the study’s abstract, which was published in-print by the journal Cannabis and Cannabinoid Research. “The complex cellular interactions regulated by the ECS suggest a potential for vascular disease and stroke prevention by augmenting central nervous and immune cell endocannabinoid signaling.”

Cannabidiol (CBD), a nonpsychoactive constituent of Cannabis, “is an immediate therapeutic candidate both for potentiating endocannabinoid signaling and for acting at multiple pharmacological targets.” According to reseachers, this “speculative synthesis explores the current state of knowledge of the ECS and suggests CBD as a therapeutic candidate for stroke prevention by exerting favorable augmentation of the homeostatic effects of the ECS and, in turn, improving the metabolic syndrome, while simultaneously stalling the development of atherosclerosis.”

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Lucky’s Market Becomes First Nationwide Grocery Store to Sale CBD Oil

Lucky’s Market has become the first nationwide grocery store to openly sale CBD oil in its stores.

Lucky’s Market – backed by Kroger – has roughly two dozen stores open throughout the United States, including in Colorado, Florida, Georgia and Wyoming. What makes Lucky’s Markets willingness to sell CBD oil so unique is that the DEA recently clarified that CBD is federally illegal, even when devoid of any THC.

“As the scientific literature indicates, cannabinoids, such as tetrahydrocannabinol (THC), cannabinol (CBN) and cannabidiol (CBD), are found in the parts of the cannabis plant that fall within the CSA definition of marijuana, such as the flowering tops, resin, and leaves”, states the DEA’s Clarification of the New Drug Code (7350) for Marijuana Extract.

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World Anti-Doping Agency Removes Cannabidiol (CBD) from Prohibited Substances List

The World Anti-Doping Agency (WADA) has officially removed cannabidiol (CBD) from their 2018 list of prohibited substances.

“Cannabidiol is no longer prohibited”, states a WADA document titled Summary of Major Modifications and Explanatory Notes, 2018 Prohibited List. WADA is however banning synthetic cannabinoids such as K2 and spice.

“Synthetic cannabidiol is not a cannabimimetic; however, cannabidiol extracted from cannabis plants may also contain varying concentrations of THC, which remains a prohibited substance,” the document notes.

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Single Dose of CBD Reduces Blood Pressure, Finds Randomized, Placebo-Controlled, Double-Blind, Crossover Study

Just a single dose of cannabidiol (CBD) reduces blood pressure, indicating it may play a role in the treatment of cardiovascular disorders, according to a new study published by the journal JCI Insight.

According to researchers, the aim of this study “was to investigate if CBD reduces BP [blood pressure] in humans.” To determine this, “Nine healthy male volunteers were given 600 mg of CBD or placebo in a randomized, placebo-controlled, double-blind, crossover study. Cardiovascular parameters were monitored using a finometer and laser Doppler.”

CBD “reduced resting systolic BP (–6 mmHg; P < 0.05) and stroke volume (–8 ml; P < 0.05), with increased heart rate (HR) and maintained cardiac output. Subjects who had taken CBD had lower BP (–5 mmHg; P < 0.05, especially before and after stress), increased HR (+10 bpm; P < 0.01), decreased stroke volume (–13 ml; P < 0.01), and a blunted forearm skin blood flow response to isometric exercise.’ In response to cold stress, “subjects who had taken CBD had blunted BP (–6 mmHg; P < 0.01) and increased HR (+7 bpm; P < 0.05), with lower total peripheral resistance.”

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Government Seeking Public Comments on Cannabidiol (CBD)

The government is seeking public comments on a variety of substances, including the cannabis-derived compound cannabidiol, commonly referred to as CBD.

Specifically, the Food and Drug Administration (FDA) is “requesting interested persons to submit comments concerning abuse potential, actual abuse, medical usefulness, trafficking, and impact of scheduling changes on availability for medical use of 17 drug substances”, including CBD. According to t he FDA, these comments “will be considered in preparing a response from the United States to the World Health Organization (WHO) regarding the abuse liability and diversion of these drugs.” WHO will use this information to consider whether to recommend that certain international restrictions be placed on these drugs. The notice requesting comments is required by the Controlled Substances Act (the CSA).

Currently CBD is defined as a schedule I controlled substance, putting it on equal footing as hard drugs like heroin. This is despite numerous states allowing CBD for medical use, and despite a plethora of research showing its medical efficacy.

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Study: CBD Blocks Opioid Reward, May Help Treat Addiction

According to a new study published in the journal Planta Medica, cannabidiol blocks the reward of opioids and as such may be useful in treating those addicted to them.

This study, conducted by researchers at the University of Mississippi and Oxford, “sought to determine whether the cannabis constituent cannabidiol attenuates the development of morphine reward in the conditioned place preference paradigm.” Separate groups of mice “received either saline or morphine in combination with one of four doses of cannabidiol using three sets of drug/no-drug conditioning trials.”

After drug-place conditioning, “morphine mice displayed robust place preference that was attenuated by 10 mg/kg cannabidiol.” Further, “when administered alone, this dose of cannabidiol was void of rewarding and aversive properties.”

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Study: CBD May Treat Psychiatric/Cognitive Symptoms Associated with Neurodegeneration

Cannabidiol (CBD) may be beneficial in the treatment of psychiatric/cognitive symptoms associated with neurodegeneration, according to a new study.

The study, published by the journal Frontiers in Pharmacology, was also published online by the U.S. National Institute of Health.

“Beneficial effects of cannabidiol (CBD) have been described for a wide range of psychiatric disorders, including anxiety, psychosis, and depression”, begins the study’s abstract. “The mechanisms responsible for these effects, however, are still poorly understood. Similar to clinical antidepressant or atypical antipsychotic drugs, recent findings clearly indicate that CBD, either acutely or repeatedly administered, induces plastic changes.”

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New Study: Cannabidiol (CBD) Exhibits Strong Anti-Seizure Properties

A new study published by the journal Neurochemical Research, and published online by the U.S. National Institute of Health, has confirmed past research that shows cannabidiol to be an anti-seizure agent.

For the study; “The National Institute of Neurological Disorders and Stroke (NINDS) funded Epilepsy Therapy Screening Program (ETSP) investigated CBD in a battery of seizure models using a refocused screening protocol aimed at identifying pharmacotherapies to address the unmet need in pharmacoresistant epilepsy”.

Applying this new screening workflow, CBD was investigated in multiple mouse and rat models of acute seizures. Following intraperitoneal (i.p.) pretreatment, “CBD produced dose-dependent protection in the acute seizure models.” In chronic models, “CBD produced dose-dependent protection in the corneal kindled mouse”.

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